The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes

Uptake of large volumes of extracellular fluid by actin-dependent macropinocytosis has an important role in infection, immunity and cancer development. A key question is how actin assembly and disassembly are coordinated around macropinosomes to allow them to form and subsequently pass through the d...

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Detalles Bibliográficos
Autores principales: Schink, Kay Oliver, Tan, Kia Wee, Spangenberg, Hélène, Martorana, Domenica, Sneeggen, Marte, Stévenin, Virginie, Enninga, Jost, Campsteijn, Coen, Raiborg, Camilla, Stenmark, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590015/
https://www.ncbi.nlm.nih.gov/pubmed/34772942
http://dx.doi.org/10.1038/s41467-021-26775-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590015/
https://www.ncbi.nlm.nih.gov/pubmed/34772942
http://dx.doi.org/10.1038/s41467-021-26775-x

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