The m(6)A “reader” YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839

N6-methyladenosine (m(6)A) is required for differentiation of human bone marrow mesenchymal stem cells (hBMSCs). However, its intrinsic mechanisms are largely unknown. To identify the possible role of m(6)A binding protein YTHDF1 in hBMSCs osteogenesis in vivo, we constructed Ythdf1 KO mice and show...

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Detalles Bibliográficos
Autores principales: Liu, Tao, Zheng, Xinfeng, Wang, Chenglong, Wang, Chuandong, Jiang, Shengdan, Li, Bo, Chen, Pengbo, Xu, Wenning, Zheng, Huoliang, Yang, Runze, Huang, Xingxu, Zhang, Xiaoling, Jiang, Leisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590051/
https://www.ncbi.nlm.nih.gov/pubmed/34772913
http://dx.doi.org/10.1038/s41419-021-04312-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590051/
https://www.ncbi.nlm.nih.gov/pubmed/34772913
http://dx.doi.org/10.1038/s41419-021-04312-4

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