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The m(6)A “reader” YTHDF1 promotes osteogenesis of bone marrow mesenchymal stem cells through translational control of ZNF839
N6-methyladenosine (m(6)A) is required for differentiation of human bone marrow mesenchymal stem cells (hBMSCs). However, its intrinsic mechanisms are largely unknown. To identify the possible role of m(6)A binding protein YTHDF1 in hBMSCs osteogenesis in vivo, we constructed Ythdf1 KO mice and show...
Autores principales: | Liu, Tao, Zheng, Xinfeng, Wang, Chenglong, Wang, Chuandong, Jiang, Shengdan, Li, Bo, Chen, Pengbo, Xu, Wenning, Zheng, Huoliang, Yang, Runze, Huang, Xingxu, Zhang, Xiaoling, Jiang, Leisheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590051/ https://www.ncbi.nlm.nih.gov/pubmed/34772913 http://dx.doi.org/10.1038/s41419-021-04312-4 |
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