Cargando…

NAMPT reduction‐induced NAD(+) insufficiency contributes to the compromised oocyte quality from obese mice

Maternal obesity is associated with multiple adverse reproductive outcomes, whereas the underlying molecular mechanisms are still not fully understood. Here, we found the reduced nicotinamide phosphoribosyl transferase (NAMPT) expression and lowered nicotinamide adenine dinucleotide (NAD(+)) content...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hengjie, Zhu, Shuai, Wu, Xinghan, Liu, Yuan, Ge, Juan, Wang, Qiang, Gu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590097/
https://www.ncbi.nlm.nih.gov/pubmed/34662475
http://dx.doi.org/10.1111/acel.13496