Changing and stable chromatin accessibility supports transcriptional overhaul during neural stem cell activation and is altered with age

Neural stem cells (NSCs) in the adult and aged brain are largely quiescent, and require transcriptional reprogramming to re‐enter the cell cycle. However, the mechanisms underlying these changes and how they are altered with age remain undefined. Here, we identify the chromatin accessibility differe...

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Detalles Bibliográficos
Autores principales: Maybury‐Lewis, Sun Y., Brown, Abigail K., Yeary, Mitchell, Sloutskin, Anna, Dhakal, Shleshma, Juven‐Gershon, Tamar, Webb, Ashley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590101/
https://www.ncbi.nlm.nih.gov/pubmed/34687484
http://dx.doi.org/10.1111/acel.13499

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590101/
https://www.ncbi.nlm.nih.gov/pubmed/34687484
http://dx.doi.org/10.1111/acel.13499

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