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MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy

Mitophagy affects the activation of hepatic stellate cells (HSCs). Mitochondria-targeted ubiquinone (MitoQ) is a mitochondria-targeted antioxidant that reduces the production of intracellular reactive oxygen species (ROS). However, its relationship with mitophagy remains unclear. This study evaluate...

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Detalles Bibliográficos
Autores principales: Dou, Shi-Ying, Zhang, Jiu-Na, Xie, Xiao-Li, Liu, Ting, Hu, Jun-Li, Jiang, Xiao-Yu, Wang, Miao-Miao, Jiang, Hui-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590110/
https://www.ncbi.nlm.nih.gov/pubmed/34825063
http://dx.doi.org/10.1515/med-2021-0394