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MitoQ inhibits hepatic stellate cell activation and liver fibrosis by enhancing PINK1/parkin-mediated mitophagy
Mitophagy affects the activation of hepatic stellate cells (HSCs). Mitochondria-targeted ubiquinone (MitoQ) is a mitochondria-targeted antioxidant that reduces the production of intracellular reactive oxygen species (ROS). However, its relationship with mitophagy remains unclear. This study evaluate...
Autores principales: | Dou, Shi-Ying, Zhang, Jiu-Na, Xie, Xiao-Li, Liu, Ting, Hu, Jun-Li, Jiang, Xiao-Yu, Wang, Miao-Miao, Jiang, Hui-Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590110/ https://www.ncbi.nlm.nih.gov/pubmed/34825063 http://dx.doi.org/10.1515/med-2021-0394 |
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