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Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis

BACKGROUND: We have recently demonstrated that serum CCL20 levels positively correlate with mean pulmonary arterial pressure in patients with systemic sclerosis (SSc). Considering a proangiogenic effect of CCL20 on endothelial cells via CCR6, the CCL20/CCR6 axis may contribute to the development of...

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Detalles Bibliográficos
Autores principales: Ikawa, Tetsuya, Miyagawa, Takuya, Fukui, Yuki, Toyama, Satoshi, Omatsu, Jun, Awaji, Kentaro, Norimatsu, Yuta, Watanabe, Yusuke, Yoshizaki, Ayumi, Sato, Shinichi, Asano, Yoshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590233/
https://www.ncbi.nlm.nih.gov/pubmed/34774095
http://dx.doi.org/10.1186/s13075-021-02667-9