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TM9SF4 is a novel regulator in lineage commitment of bone marrow mesenchymal stem cells to either osteoblasts or adipocytes

BACKGROUND: Osteoporosis is a common bone disease in elderly population caused by imbalanced bone formation and bone resorption. Mesenchymal stem cells (MSCs) are responsible for maintaining this bone homeostasis. The phenotype of transmembrane 9 superfamily 4 (TM9SF4) knockout mice suggests a relat...

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Detalles Bibliográficos
Autores principales: Yu, Libo, Xie, Mingxu, Zhang, Fengjie, Wan, Chao, Yao, Xiaoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590266/
https://www.ncbi.nlm.nih.gov/pubmed/34774100
http://dx.doi.org/10.1186/s13287-021-02636-8