CYP2J2 and EETs protect against pulmonary arterial hypertension with lung ischemia–reperfusion injury in vivo and in vitro

BACKGROUND: Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to epoxyeicosatrienoic acids (EETs), which exert anti-inflammatory, anti-apoptotic, pro-proliferative, and antioxidant effects on the cardiovascular system. However, the role of CYP2J2 and EETs in pulmonary arterial hy...

Descripción completa

Detalles Bibliográficos
Autores principales: Ding, Yun, Tu, Pengjie, Chen, Yiyong, Huang, Yangyun, Pan, Xiaojie, Chen, Wenshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590292/
https://www.ncbi.nlm.nih.gov/pubmed/34774051
http://dx.doi.org/10.1186/s12931-021-01891-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590292/
https://www.ncbi.nlm.nih.gov/pubmed/34774051
http://dx.doi.org/10.1186/s12931-021-01891-w

Ejemplares similares