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CYP2J2 and EETs protect against pulmonary arterial hypertension with lung ischemia–reperfusion injury in vivo and in vitro

BACKGROUND: Cytochrome P450 epoxygenase 2J2 (CYP2J2) metabolizes arachidonic acid to epoxyeicosatrienoic acids (EETs), which exert anti-inflammatory, anti-apoptotic, pro-proliferative, and antioxidant effects on the cardiovascular system. However, the role of CYP2J2 and EETs in pulmonary arterial hy...

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Detalles Bibliográficos
Autores principales:	Ding, Yun, Tu, Pengjie, Chen, Yiyong, Huang, Yangyun, Pan, Xiaojie, Chen, Wenshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590292/ https://www.ncbi.nlm.nih.gov/pubmed/34774051 http://dx.doi.org/10.1186/s12931-021-01891-w

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