Tyrosine 136 phosphorylation of α-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2

Serine 129 (S129) phosphorylation of α-synuclein (αSyn) is a central feature of Lewy body (LB) disease pathology. Although the neighboring tyrosine residues Y125, Y133, and Y136 are also phosphorylation sites, little is known regarding potential roles of phosphorylation cross-talk between these site...

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Detalles Bibliográficos
Autores principales: Sano, Kazunori, Iwasaki, Yasushi, Yamashita, Yuta, Irie, Keiichi, Hosokawa, Masato, Satoh, Katsuya, Mishima, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590312/
https://www.ncbi.nlm.nih.gov/pubmed/34772466
http://dx.doi.org/10.1186/s40478-021-01281-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590312/
https://www.ncbi.nlm.nih.gov/pubmed/34772466
http://dx.doi.org/10.1186/s40478-021-01281-9

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