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The Anti-Inflammation and Anti-Nociception Effect of Ketoprofen in Rats Could Be Strengthened Through Co-Delivery of a H(2)S Donor, S-Propargyl-Cysteine

PURPOSE: Ketoprofen (KETO) is a traditional non-steroidal anti-inflammatory drug (NSAIDs) with good analgesic and antipyretic effects. However, as NASIDs, the toxicity of KETO towards gastrointestinal (GI) system might limit its clinical use. S-propargyl-cysteine (SPRC) is an excellent endogenous H(...

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Detalles Bibliográficos
Autores principales: Yu, Yue, Yang, Qinyan, Wang, Zhou, Ding, Qian, Li, Meng, Fang, Yudong, He, Qida, Zhu, Yi Zhun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590460/
https://www.ncbi.nlm.nih.gov/pubmed/34785926
http://dx.doi.org/10.2147/JIR.S333326