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PRMT1-mediated EZH2 methylation promotes breast cancer cell proliferation and tumorigenesis

Protein arginine methyltransferase 1 (PRMT1) is able to promote breast cancer cell proliferation. However, the detailed mechanisms of PRMT1-mediated breast cancer cell proliferation are largely unknown. In this study, we reveal that PRMT1-mediated methylation of EZH2 at the R342 site (meR342-EZH2) h...

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Detalles Bibliográficos
Autores principales: Li, Zhongwei, Wang, Diandian, Chen, Xintian, Wang, Wenwen, Wang, Pengfei, Hou, Pingfu, Li, Minle, Chu, Sufang, Qiao, Shuxi, Zheng, Junnian, Bai, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590688/
https://www.ncbi.nlm.nih.gov/pubmed/34775498
http://dx.doi.org/10.1038/s41419-021-04381-5