Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression

HER2-positive breast cancers may lose HER2 expression in recurrences and metastases. In this work, we studied cell lines derived from two transgenic mammary tumors driven by human HER2 that showed different dynamics of HER2 status. MamBo89HER2(stable) cell line displayed high and stable HER2 express...

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Detalles Bibliográficos
Autores principales: Giusti, Veronica, Ruzzi, Francesca, Landuzzi, Lorena, Ianzano, Marianna L., Laranga, Roberta, Nironi, Elena, Scalambra, Laura, Nicoletti, Giordano, De Giovanni, Carla, Olivero, Martina, Arigoni, Maddalena, Calogero, Raffaele, Nanni, Patrizia, Palladini, Arianna, Lollini, Pier-Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590694/
https://www.ncbi.nlm.nih.gov/pubmed/34775465
http://dx.doi.org/10.1038/s41389-021-00360-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590694/
https://www.ncbi.nlm.nih.gov/pubmed/34775465
http://dx.doi.org/10.1038/s41389-021-00360-9

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