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Cellular retinol binding protein-1 inhibits cancer stemness via upregulating WIF1 to suppress Wnt/β-catenin pathway in hepatocellular carcinoma

BACKGROUND: CRBP-1, a cytosolic chaperone of vitamin A, is identified in a serious number of cancers; however, its biological role in hepatocellular carcinoma (HCC) needs to be further explored. The aim of our present study is to explore the roles and mechanisms of CRBP-1 in regulating liver cancer...

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Detalles Bibliográficos
Autores principales: Liu, Xiangye, Shan, Wenhua, Li, Tingting, Gao, Xiaoge, Kong, Fanyun, You, Hongjuan, Kong, Delong, Qiao, Shuxi, Tang, Renxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590789/
https://www.ncbi.nlm.nih.gov/pubmed/34775955
http://dx.doi.org/10.1186/s12885-021-08967-2