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Identifying a novel biological mechanism for alcohol addiction associated with circRNA networks acting as potential miRNA sponges

Our lab and others have shown that chronic alcohol use leads to gene and miRNA expression changes across the mesocorticolimbic (MCL) system. Circular RNAs (circRNAs) are noncoding RNAs that form closed‐loop structures and are reported to alter gene expression through miRNA sequestration, thus provid...

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Detalles Bibliográficos
Autores principales: Vornholt, Eric, Drake, John, Mamdani, Mohammed, McMichael, Gowon, Taylor, Zachary N., Bacanu, Silviu‐Alin, Miles, Michael F., Vladimirov, Vladimir I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590811/
https://www.ncbi.nlm.nih.gov/pubmed/34164896
http://dx.doi.org/10.1111/adb.13071