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Transdermal Delivery of Telmisartan: Formulation, in vitro, ex vivo, Iontophoretic Permeation Enhancement and Comparative Pharmacokinetic Study in Rats

PURPOSE: The purpose of this study was to prepare telmisartan transethosomes, incorporate them into a gel, evaluate them for in vitro drug release and in vivo permeation using iontophoresis to enhance their transdermal delivery. MATERIALS AND METHODS: TE formulae were prepared using various surfacta...

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Detalles Bibliográficos
Autores principales: Teaima, Mahmoud, Abdelmonem, Rehab, Adel, Yomna A, El-Nabarawi, Mohamed A, El-Nawawy, Tayseer M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8590984/
https://www.ncbi.nlm.nih.gov/pubmed/34785889
http://dx.doi.org/10.2147/DDDT.S327860