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KRAS mutation: from undruggable to druggable in cancer

Cancer is the leading cause of death worldwide, and its treatment and outcomes have been dramatically revolutionised by targeted therapies. As the most frequently mutated oncogene, Kirsten rat sarcoma viral oncogene homologue (KRAS) has attracted substantial attention. The understanding of KRAS is c...

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Detalles Bibliográficos
Autores principales: Huang, Lamei, Guo, Zhixing, Wang, Fang, Fu, Liwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591115/
https://www.ncbi.nlm.nih.gov/pubmed/34776511
http://dx.doi.org/10.1038/s41392-021-00780-4