Targeting Wnt Signaling in the Tumor Immune Microenvironment to Enhancing EpCAM CAR T-Cell therapy

Colorectal cancer (CRC) patients are still lacking viable treatments. Chimeric antigen receptor (CAR) T cells have shown promise in hematologic malignancies, but their efficacy in solid tumors has been limited due to the immunosuppressive tumor microenvironment. We found that cancer antigen- EpCAM e...

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Detalles Bibliográficos
Autores principales: Li, Weizhen, Zhou, Yang, Wu, Zhongen, Shi, Yaoping, Tian, Enming, Zhu, Yingqi, Wang, Tao, Dou, Wei, Meng, Xiangjing, Chen, Ming, Zhai, Bo, Zhu, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591126/
https://www.ncbi.nlm.nih.gov/pubmed/34790117
http://dx.doi.org/10.3389/fphar.2021.724306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591126/
https://www.ncbi.nlm.nih.gov/pubmed/34790117
http://dx.doi.org/10.3389/fphar.2021.724306

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