Anti-Tumor Activity of AZD4547 Against NTRK1 Fusion Positive Cancer Cells Through Inhibition of NTRKs

Inhibitors of tropomyosin-related kinases (TRKs) display remarkable outcomes in the regression of cancers harboring the Neurotrophin Receptors Tyrosine Kinase (NTRK) fusion gene. As a result, TRKs have become attractive targets in anti-cancer drug discovery programs. Here, we demonstrate that AZD454...

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Detalles Bibliográficos
Autores principales: Cho, Hanna, Kim, Namkyoung, Murakami, Takashi, Sim, Taebo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591201/
https://www.ncbi.nlm.nih.gov/pubmed/34790577
http://dx.doi.org/10.3389/fonc.2021.757598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591201/
https://www.ncbi.nlm.nih.gov/pubmed/34790577
http://dx.doi.org/10.3389/fonc.2021.757598

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