Stimulation of the PD-1 Pathway Decreases Atherosclerotic Lesion Development in Ldlr Deficient Mice

Aim: Signaling through the coinhibitory programmed death (PD)-1/PD-L1 pathway regulates T cell responses and can inhibit ongoing immune responses. Inflammation is a key process in the development of atherosclerosis, the underlying cause for the majority of cardiovascular diseases. Dampening the exce...

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Detalles Bibliográficos
Autores principales: Grievink, Hendrika W., Smit, Virginia, Verwilligen, Robin A. F., Bernabé Kleijn, Mireia N. A., Smeets, Diede, Binder, Christoph J., Yagita, Hideo, Moerland, Matthijs, Kuiper, Johan, Bot, Ilze, Foks, Amanda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591266/
https://www.ncbi.nlm.nih.gov/pubmed/34790707
http://dx.doi.org/10.3389/fcvm.2021.740531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591266/
https://www.ncbi.nlm.nih.gov/pubmed/34790707
http://dx.doi.org/10.3389/fcvm.2021.740531

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