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The RNA Methyltransferase METTL3 Promotes Endothelial Progenitor Cell Angiogenesis in Mandibular Distraction Osteogenesis via the PI3K/AKT Pathway

Distraction osteogenesis (DO) is used to treat large bone defects in the field of oral and maxillofacial surgery. Successful DO-mediated bone regeneration is dependent upon angiogenesis, and endothelial progenitor cells (EPCs) are key mediators of angiogenic processes. The N6-methyladenosine (m(6)A)...

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Detalles Bibliográficos
Autores principales: Jiang, Weidong, Zhu, Peiqi, Huang, Fangfang, Zhao, Zhenchen, Zhang, Tao, An, Xiaoning, Liao, Fengchun, Guo, Lina, Liu, Yan, Zhou, Nuo, Huang, Xuanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591310/
https://www.ncbi.nlm.nih.gov/pubmed/34790657
http://dx.doi.org/10.3389/fcell.2021.720925