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Identifying tumorigenic non-coding mutations through altered cis-regulation

Identification of non-coding mutations driving tumorigenesis requires alternative approaches to coding mutations. Enriched associations between mutated regulatory elements and altered cis-regulation in tumors are a promising approach to stratify candidate non-coding driver mutations. Here we provide...

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Detalles Bibliográficos
Autores principales: Cheng, Zhongshan, Vermeulen, Michael, Rollins-Green, Micheal, Babak, Tomas, DeVeale, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591365/
https://www.ncbi.nlm.nih.gov/pubmed/34816127
http://dx.doi.org/10.1016/j.xpro.2021.100934