SAG therapy restores bone growth and reduces enchondroma incidence in a model of skeletal chondrodysplasias caused by Ihh deficiency

Inactivation mutations in the Indian hedgehog (Ihh) gene in humans cause numerous skeletal chondrodysplasias, including acrocapitofemoral dysplasia, brachydactyly type A1, and human short stature. The lack of an appropriate human-relevant model to accurately represent these chondrodysplasias has ham...

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Detalles Bibliográficos
Autores principales: Li, Xinhua, Yang, Shuting, Chinipardaz, Zahra, Koyama, Eiki, Yang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591400/
https://www.ncbi.nlm.nih.gov/pubmed/34820473
http://dx.doi.org/10.1016/j.omtm.2021.09.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591400/
https://www.ncbi.nlm.nih.gov/pubmed/34820473
http://dx.doi.org/10.1016/j.omtm.2021.09.015

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