Stabilin receptors clear LPS and control systemic inflammation

Lipopolysaccharides (LPSs) cause lethal endotoxemia if not rapidly cleared from blood circulation. Liver sinusoidal endothelial cells (LSEC) systemically clear LPS by unknown mechanisms. We discovered that LPS clearance through LSEC involves endocytosis and lysosomal inactivation via Stabilin-1 and...

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Detalles Bibliográficos
Autores principales: Cabral, Fatima, Al-Rahem, Mustafa, Skaggs, John, Thomas, Thushara A., Kumar, Naresh, Wu, Qian, Fadda, Paolo, Yu, Lianbo, Robinson, John M., Kim, Jonghan, Pandey, Ekta, Sun, Xinghui, Jarjour, Wael N., Rajaram, Murugesan V.S., Harris, Edward N., Ganesan, Latha P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591421/
https://www.ncbi.nlm.nih.gov/pubmed/34816100
http://dx.doi.org/10.1016/j.isci.2021.103337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591421/
https://www.ncbi.nlm.nih.gov/pubmed/34816100
http://dx.doi.org/10.1016/j.isci.2021.103337

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