Cargando…

Stabilin receptors clear LPS and control systemic inflammation

Lipopolysaccharides (LPSs) cause lethal endotoxemia if not rapidly cleared from blood circulation. Liver sinusoidal endothelial cells (LSEC) systemically clear LPS by unknown mechanisms. We discovered that LPS clearance through LSEC involves endocytosis and lysosomal inactivation via Stabilin-1 and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cabral, Fatima, Al-Rahem, Mustafa, Skaggs, John, Thomas, Thushara A., Kumar, Naresh, Wu, Qian, Fadda, Paolo, Yu, Lianbo, Robinson, John M., Kim, Jonghan, Pandey, Ekta, Sun, Xinghui, Jarjour, Wael N., Rajaram, Murugesan V.S., Harris, Edward N., Ganesan, Latha P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591421/ https://www.ncbi.nlm.nih.gov/pubmed/34816100 http://dx.doi.org/10.1016/j.isci.2021.103337

Ejemplares similares

Ligand Binding and Signaling of HARE/Stabilin-2
por: Harris, Edward N., et al.
Publicado: (2019)

Reduction of Stabilin-2 Contributes to a Protection Against Atherosclerosis
por: Kayashima, Yukako, et al.
Publicado: (2022)

Chloroquine and cytosolic galectins affect endosomal escape of antisense oligonucleotides after Stabilin-mediated endocytosis
por: Pandey, Ekta, et al.
Publicado: (2023)

Stabilin-1 and Stabilin-2 are specific receptors for the cellular internalization of phosphorothioate-modified antisense oligonucleotides (ASOs) in the liver
por: Miller, Colton M., et al.
Publicado: (2016)

Identifying Stabilin-1 and Stabilin-2 Double Knockouts in Reproduction and Placentation: A Descriptive Study
por: Kim, Soon-Young, et al.
Publicado: (2020)

Nontuberculous mycobacterium M. avium infection predisposes aged mice to cardiac abnormalities and inflammation
por: Headley, Colwyn A., et al.
Publicado: (2019)

Stabilin Receptors: Role as Phosphatidylserine Receptors
por: Park, Seung-Yoon, et al.
Publicado: (2019)

Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2
por: Holte, Christopher, et al.
Publicado: (2023)

Role of the Hyaluronan Receptor, Stabilin-2/HARE, in Health and Disease
por: Harris, Edward N., et al.
Publicado: (2020)

Multifunctional Receptor Stabilin-1 in Homeostasis and Disease
por: Kzhyshkowska, Julia
Publicado: (2010)

Deficiency for scavenger receptors Stabilin‐1 and Stabilin‐2 leads to age‐dependent renal and hepatic depositions of fasciclin domain proteins TGFBI and Periostin in mice
por: Leibing, Thomas, et al.
Publicado: (2023)

Aging influences the cardiac macrophage phenotype and function during steady state and during inflammation
por: Esfahani, Noushin Saljoughian, et al.
Publicado: (2021)

Stabilin-1, a homeostatic scavenger receptor with multiple functions
por: Kzhyshkowska, Julia, et al.
Publicado: (2006)

Structural Determinants for the Interactions of Chemically Modified Nucleic Acids with the Stabilin-2 Clearance Receptor
por: Gaus, Hans, et al.
Publicado: (2018)

Influenza A virus modulates ACE2 expression and SARS-CoV-2 infectivity in human cardiomyocytes
por: Wu, Qian, et al.
Publicado: (2022)

Cardiac Electrical and Structural Changes During Bacterial Infection: An Instructive Model to Study Cardiac Dysfunction in Sepsis
por: Makara, Michael A., et al.
Publicado: (2016)

Enhanced Antibody Production in Clever-1/Stabilin-1–Deficient Mice
por: Dunkel, Johannes, et al.
Publicado: (2018)

The Role of Stabilin-1 in Lymphocyte Trafficking and Macrophage Scavenging in the Liver Microenvironment
por: Patten, Daniel A., et al.
Publicado: (2019)

Systemic Glycosaminoglycan Clearance by HARE/Stabilin-2 Activates Intracellular Signaling
por: Weigel, Paul H.
Publicado: (2020)

Association of Differentially Altered Liver Fibrosis with Deposition of TGFBi in Stabilin-Deficient Mice
por: Krzistetzko, Jessica, et al.
Publicado: (2023)

Mouse Liver Sinusoidal Endothelium Eliminates HIV-Like Particles from Blood at a Rate of 100 Million per Minute by a Second-Order Kinetic Process
por: Mates, Jessica M., et al.
Publicado: (2017)

Stabilin-2 modulates the efficiency of myoblast fusion during myogenic differentiation and muscle regeneration
por: Park, Seung-Yoon, et al.
Publicado: (2016)

Aging heart and infection
por: Headley, Colwyn, et al.
Publicado: (2019)

Titanium Nanoparticles Enhance Production and Suppress Stabilin-1-Mediated Clearance of GDF-15 in Human Primary Macrophages
por: Silva-Bermudez, Lina S., et al.
Publicado: (2021)

HOXC9 Regulates Formation of Parachordal Lymphangioplasts and the Thoracic Duct in Zebrafish via Stabilin 2
por: Stoll, Sandra J., et al.
Publicado: (2013)

Hyaluronic Acid Receptor Stabilin-2 Regulates Erk Phosphorylation and Arterial - Venous Differentiation in Zebrafish
por: Rost, Megan S., et al.
Publicado: (2014)

Microlocalization and clinical significance of stabilin-1(+) macrophages in treatment-naïve patients with urothelial carcinoma of the bladder
por: Wang, Bo, et al.
Publicado: (2019)

High expression of Stabilin-2 predicts poor prognosis in non-small-cell lung cancer
por: Yong, Juanjuan, et al.
Publicado: (2021)

BRAF(V600E) Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages
por: Spourquet, Catherine, et al.
Publicado: (2022)

Endosomal Escape of Antisense Oligonucleotides Internalized by Stabilin Receptors Is Regulated by Rab5C and EEA1 During Endosomal Maturation
por: Miller, Colton M., et al.
Publicado: (2018)

Stabilin-1 is expressed in human breast cancer and supports tumor growth in mammary adenocarcinoma mouse model
por: Riabov, Vladimir, et al.
Publicado: (2016)

Novel function of stabilin-2 in myoblast fusion: the recognition of extracellular phosphatidylserine as a “fuse-me” signal
por: Kim, Go-Woon, et al.
Publicado: (2016)

Accumulation of stabilin-1 positive macrophages in the early stage of gastric cancer is associated with short cumulative survival
por: Yin, Shui-Ping, et al.
Publicado: (2020)

A Novel Inflammatory Dendritic Cell That Is Abundant and Contiguous to T Cells in the Kidneys of Patients With Lupus Nephritis
por: Parikh, Samir V., et al.
Publicado: (2021)

The liver sinusoidal endothelial cell hyaluronan receptor and its homolog, stabilin-1 – Their roles (known and unknown) in endocytosis
por: McCourt, Peter AG, et al.
Publicado: (2004)

Tumor-associated macrophages respond to chemotherapy by detrimental transcriptional reprogramming and suppressing stabilin-1 mediated clearance of EGF
por: Larionova, Irina, et al.
Publicado: (2023)

Discovery of the Liver Hyaluronan Receptor for Endocytosis (HARE) and Its Progressive Emergence as the Multi-Ligand Scavenger Receptor Stabilin-2
por: Weigel, Paul H.
Publicado: (2019)

The therapeutic effects of gingival mesenchymal stem cells and their exosomes in a chimeric model of rheumatoid arthritis
por: Bruckner, Shane, et al.
Publicado: (2023)

Therapeutic Effects of Gingival Mesenchymal Stem Cells and Their Exosomes in a Chimeric Model of Rheumatoid Arthritis
por: Bruckner, Shane, et al.
Publicado: (2023)

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion
por: Hamoud, Noumeira, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5v8qc8pdlf05hf5u4a9has1lej