The CRL4(DCAF1) cullin‐RING ubiquitin ligase is activated following a switch in oligomerization state

The cullin‐4‐based RING‐type (CRL4) family of E3 ubiquitin ligases functions together with dedicated substrate receptors. Out of the ˜29 CRL4 substrate receptors reported, the DDB1‐ and CUL4‐associated factor 1 (DCAF1) is essential for cellular survival and growth, and its deregulation has been impl...

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Detalles Bibliográficos
Autores principales: Mohamed, Weaam I, Schenk, Andreas D, Kempf, Georg, Cavadini, Simone, Basters, Anja, Potenza, Alessandro, Abdul Rahman, Wassim, Rabl, Julius, Reichermeier, Kurt, Thomä, Nicolas H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591539/
https://www.ncbi.nlm.nih.gov/pubmed/34595758
http://dx.doi.org/10.15252/embj.2021108008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591539/
https://www.ncbi.nlm.nih.gov/pubmed/34595758
http://dx.doi.org/10.15252/embj.2021108008

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