Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis

Mutations in VAV1, a gene that encodes a multifunctional protein important for lymphocytes, are found at different frequencies in peripheral T‐cell lymphoma (PTCL), non‐small cell lung cancer, and other tumors. However, their pathobiological significance remains unsettled. After cataloguing 51 cance...

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Detalles Bibliográficos
Autores principales: Robles‐Valero, Javier, Fernández‐Nevado, Lucía, Lorenzo‐Martín, L Francisco, Cuadrado, Myriam, Fernández‐Pisonero, Isabel, Rodríguez‐Fdez, Sonia, Astorga‐Simón, Elsa N, Abad, Antonio, Caloto, Rubén, Bustelo, Xosé R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591544/
https://www.ncbi.nlm.nih.gov/pubmed/34617326
http://dx.doi.org/10.15252/embj.2021108125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591544/
https://www.ncbi.nlm.nih.gov/pubmed/34617326
http://dx.doi.org/10.15252/embj.2021108125

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