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Cancer‐associated mutations in VAV1 trigger variegated signaling outputs and T‐cell lymphomagenesis
Mutations in VAV1, a gene that encodes a multifunctional protein important for lymphocytes, are found at different frequencies in peripheral T‐cell lymphoma (PTCL), non‐small cell lung cancer, and other tumors. However, their pathobiological significance remains unsettled. After cataloguing 51 cance...
Autores principales: | Robles‐Valero, Javier, Fernández‐Nevado, Lucía, Lorenzo‐Martín, L Francisco, Cuadrado, Myriam, Fernández‐Pisonero, Isabel, Rodríguez‐Fdez, Sonia, Astorga‐Simón, Elsa N, Abad, Antonio, Caloto, Rubén, Bustelo, Xosé R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591544/ https://www.ncbi.nlm.nih.gov/pubmed/34617326 http://dx.doi.org/10.15252/embj.2021108125 |
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