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Effect of spironolactone use in pulmonary arterial hypertension – analysis from pivotal trial databases

Spironolactone, a common diuretic used in the treatment of pulmonary arterial hypertension (PAH), improves cardiopulmonary hemodynamics by attenuating the adverse effects of hyperaldosteronism on endothelin type-B receptor function within pulmonary endothelial cells. Spironolactone has demonstrated...

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Detalles Bibliográficos
Autores principales: Safdar, Zeenat, Cho, Eunah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591657/
https://www.ncbi.nlm.nih.gov/pubmed/34790347
http://dx.doi.org/10.1177/20458940211045618