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Immunohistochemistry as an accurate tool for the assessment of BRAF V600E and TP53 mutations in primary and metastatic melanoma

Metastatic melanoma is a fatal disease with poor prognosis. Ever since targeted therapy against oncogenic BRAF was approved, molecular profiling has become an integral part of the management of such patients. While molecular testing is not available in all pathology laboratories, immunohistochemistr...

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Detalles Bibliográficos
Autores principales: Rusu, Stefan, Verocq, Camille, Trepant, Anne Laure, Maris, Calliope, De Nève, Nancy, Blanchard, Oriane, Van Campenhout, Claude, De Clercq, Sarah, Rorive, Sandrine, Cotoi, Ovidiu Simion, Decaestecker, Christine, Salmon, Isabelle, D'Haene, Nicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591695/
https://www.ncbi.nlm.nih.gov/pubmed/34790354
http://dx.doi.org/10.3892/mco.2021.2432