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New Selective Inhibitors of ERG Positive Prostate Cancer: ERGi-USU-6 Salt Derivatives

[Image: see text] Prostate cancer is among the leading causes of cancer related death of men in the United States. The ERG gene fusion leading to overexpression of near full-length ERG transcript and protein represents most prevalent (50–65%) prostate cancer driver gene alterations. The ERG oncoprot...

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Detalles Bibliográficos
Autores principales: Eldhose, Binil, Pandrala, Mallesh, Xavier, Charles, Mohamed, Ahmed A., Srivastava, Shiv, Sunkara, Anu D., Dobi, Albert, Malhotra, Sanjay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591719/
https://www.ncbi.nlm.nih.gov/pubmed/34790292
http://dx.doi.org/10.1021/acsmedchemlett.1c00308