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The Discovery of Conformationally Constrained Bicyclic Peptidomimetics as Potent Hepatitis C NS5A Inhibitors

[Image: see text] HCV NS5A inhibitors are the backbone of directly acting antiviral treatments against the hepatitis C virus (HCV). While these therapies are generally highly curative, they are less effective in some specific HCV patient populations. In the search for broader-acting HCV NS5A inhibit...

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Detalles Bibliográficos
Autores principales: Kazmierski, Wieslaw M., Miriyala, Nagaraju, Johnson, David K., Baskaran, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591741/
https://www.ncbi.nlm.nih.gov/pubmed/34790290
http://dx.doi.org/10.1021/acsmedchemlett.1c00391