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Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC)
OBJECTIVE(S): Duchene muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations in the DMD gene, resulting in the absence of dystrophin expression leading to membrane fragility and myofibril necrosis in the muscle cells. Because of progressive weakness in the skeletal and c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591754/ https://www.ncbi.nlm.nih.gov/pubmed/34804433 http://dx.doi.org/10.22038/IJBMS.2021.54711.12269 |