Dystrophin gene editing by CRISPR/Cas9 system in human skeletal muscle cell line (HSkMC)

OBJECTIVE(S): Duchene muscular dystrophy (DMD) is a progressive neuromuscular disease caused by mutations in the DMD gene, resulting in the absence of dystrophin expression leading to membrane fragility and myofibril necrosis in the muscle cells. Because of progressive weakness in the skeletal and c...

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Detalles Bibliográficos
Autores principales: Dara, Mahintaj, Razban, Vahid, Mazloomrezaei, Mohsen, Ranjbar, Maryam, Nourigorji, Marjan, Dianatpour, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591754/
https://www.ncbi.nlm.nih.gov/pubmed/34804433
http://dx.doi.org/10.22038/IJBMS.2021.54711.12269

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