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CircRNA-DOPEY2 enhances the chemosensitivity of esophageal cancer cells by inhibiting CPEB4-mediated Mcl-1 translation

BACKGROUND: Cisplatin-based chemotherapy is a mainstay systematic therapy for advanced esophageal squamous cell carcinoma (ESCC), and cisplatin resistance, which is not uncommon, is the major barrier to improving patient outcomes. Circular RNAs (circRNAs) are novel noncoding RNAs that are implicated...

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Detalles Bibliográficos
Autores principales: Liu, Zhenchuan, Gu, Shaorui, Wu, Kaiqin, Li, Lei, Dong, Chenglai, Wang, Wenli, Zhou, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591801/
https://www.ncbi.nlm.nih.gov/pubmed/34781999
http://dx.doi.org/10.1186/s13046-021-02149-5