Heparin interacts with the main protease of SARS-CoV-2 and inhibits its activity

The ability of SARS-CoV-2 to replicate in host cells is dependent on its main protease (M(pro), also called 3CLpro) that cut the viral precursor polyproteins and is a major target for antiviral drug design. Here, we showed that heparin interacts with the M(pro) of SARS-CoV-2 and inhibits its activit...

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Detalles Bibliográficos
Autores principales: Li, Jinwen, Zhang, Yantao, Pang, Huimin, Li, Shu Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591854/
https://www.ncbi.nlm.nih.gov/pubmed/34815178
http://dx.doi.org/10.1016/j.saa.2021.120595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591854/
https://www.ncbi.nlm.nih.gov/pubmed/34815178
http://dx.doi.org/10.1016/j.saa.2021.120595

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