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Lamin C is required to establish genome organization after mitosis

BACKGROUND: The dynamic 3D organization of the genome is central to gene regulation and development. The nuclear lamina influences genome organization through the tethering of lamina-associated domains (LADs) to the nuclear periphery. Evidence suggests that lamins A and C are the predominant lamins...

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Detalles Bibliográficos
Autores principales: Wong, Xianrong, Hoskins, Victoria E., Melendez-Perez, Ashley J., Harr, Jennifer C., Gordon, Molly, Reddy, Karen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591896/
https://www.ncbi.nlm.nih.gov/pubmed/34775987
http://dx.doi.org/10.1186/s13059-021-02516-7