Discovery of new TLR7 agonists by a combination of statistical learning-based QSAR, virtual screening, and molecular dynamics

Search for new antiviral medications has surged in the past two years due to the COVID-19 crisis. Toll-like receptor 7 (TLR7) is among one of the most important TLR proteins of innate immunity that is responsible for broad antiviral response and immune system control. TLR7 agonists, as both vaccine...

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Detalles Bibliográficos
Autores principales: Abiri, Ardavan, Rezaei, Masoud, Zeighami, Mohammad Hossein, Vaezpour, Younes, Dehghan, Leili, KhorramGhahfarokhi, Maedeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591993/
https://www.ncbi.nlm.nih.gov/pubmed/34805481
http://dx.doi.org/10.1016/j.imu.2021.100787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591993/
https://www.ncbi.nlm.nih.gov/pubmed/34805481
http://dx.doi.org/10.1016/j.imu.2021.100787

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