Cargando…
Discovery of new TLR7 agonists by a combination of statistical learning-based QSAR, virtual screening, and molecular dynamics
Search for new antiviral medications has surged in the past two years due to the COVID-19 crisis. Toll-like receptor 7 (TLR7) is among one of the most important TLR proteins of innate immunity that is responsible for broad antiviral response and immune system control. TLR7 agonists, as both vaccine...
Autores principales: | Abiri, Ardavan, Rezaei, Masoud, Zeighami, Mohammad Hossein, Vaezpour, Younes, Dehghan, Leili, KhorramGhahfarokhi, Maedeh |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8591993/ https://www.ncbi.nlm.nih.gov/pubmed/34805481 http://dx.doi.org/10.1016/j.imu.2021.100787 |
Ejemplares similares
-
QSAR-Based Virtual Screening: Advances and Applications in Drug Discovery
por: Neves, Bruno J., et al.
Publicado: (2018) -
A review on function and side effects of systemic corticosteroids used in high-grade COVID-19 to prevent cytokine storms
por: Langarizadeh, Mohammad Amin, et al.
Publicado: (2021) -
Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
por: Tsou, Lun K., et al.
Publicado: (2020) -
Evaluation of QSAR Equations for Virtual Screening
por: Spiegel, Jacob, et al.
Publicado: (2020) -
Discovery of novel TLR modulators by Molecular Modeling and Virtual Screening
por: Murgueitio, Manuela S, et al.
Publicado: (2012)