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A mouse model of hypoplastic left heart syndrome demonstrating left heart hypoplasia and retrograde aortic arch flow

In hypoplastic left heart syndrome (HLHS), the mechanisms leading to left heart hypoplasia and their associated fetal abnormalities are largely unknown. Current animal models have limited utility in resolving these questions as they either do not fully reproduce the cardiac phenotype, do not survive...

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Detalles Bibliográficos
Autores principales: Rahman, Anum, DeYoung, Taylor, Cahill, Lindsay S., Yee, Yohan, Debebe, Sarah K., Botelho, Owen, Seed, Mike, Chaturvedi, Rajiv R., Sled, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592017/
https://www.ncbi.nlm.nih.gov/pubmed/34514502
http://dx.doi.org/10.1242/dmm.049077