Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

BACKGROUND/AIMS: There is growing interest in the use of adaptive designs to improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential experiment using cost and outcome data from the ProFHER pragmatic trial. We assess the model’s potential for delivering...

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Detalles Bibliográficos
Autores principales: Forster, Martin, Brealey, Stephen, Chick, Stephen, Keding, Ada, Corbacho, Belen, Alban, Andres, Pertile, Paolo, Rangan, Amar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592107/
https://www.ncbi.nlm.nih.gov/pubmed/34407641
http://dx.doi.org/10.1177/17407745211032909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592107/
https://www.ncbi.nlm.nih.gov/pubmed/34407641
http://dx.doi.org/10.1177/17407745211032909

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