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Cost-effective clinical trial design: Application of a Bayesian sequential model to the ProFHER pragmatic trial

BACKGROUND/AIMS: There is growing interest in the use of adaptive designs to improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential experiment using cost and outcome data from the ProFHER pragmatic trial. We assess the model’s potential for delivering...

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Detalles Bibliográficos
Autores principales:	Forster, Martin, Brealey, Stephen, Chick, Stephen, Keding, Ada, Corbacho, Belen, Alban, Andres, Pertile, Paolo, Rangan, Amar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592107/ https://www.ncbi.nlm.nih.gov/pubmed/34407641 http://dx.doi.org/10.1177/17407745211032909

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