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Development of physiologically‐based pharmacokinetic models for standard of care and newer tuberculosis drugs

Tuberculosis (TB) remains a global health problem and there is an ongoing effort to develop more effective therapies and new combination regimes that can reduce duration of treatment. The purpose of this study was to demonstrate utility of a physiologically‐based pharmacokinetic modeling approach to...

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Detalles Bibliográficos
Autores principales: Humphries, Helen, Almond, Lisa, Berg, Alexander, Gardner, Iain, Hatley, Oliver, Pan, Xian, Small, Ben, Zhang, Mian, Jamei, Masoud, Romero, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592506/
https://www.ncbi.nlm.nih.gov/pubmed/34623770
http://dx.doi.org/10.1002/psp4.12707