Early reduction in PD-L1 expression predicts faster treatment response in human cutaneous leishmaniasis

Cutaneous leishmaniasis (CL) is caused by Leishmania donovani in Sri Lanka. Pentavalent antimonials (e.g., sodium stibogluconate [SSG]) remain first-line drugs for CL with no new effective treatments emerging. We studied whole blood and lesion transcriptomes from Sri Lankan patients with CL at prese...

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Detalles Bibliográficos
Autores principales: Dey, Nidhi S., Senaratne, Sujai, Somaratne, Vijani, Madarasinghe, Nayani P., Seneviratne, Bimalka, Forrester, Sarah, Montes de Oca, Marcela, Reis, Luiza Campos, Moulik, Srija, Walrad, Pegine B., Chatterjee, Mitali, Goto, Hiro, Wickremasinghe, Renu, Lagos, Dimitris, Kaye, Paul M., Ranasinghe, Shalindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Concise Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592550/
https://www.ncbi.nlm.nih.gov/pubmed/34609968
http://dx.doi.org/10.1172/JCI142765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592550/
https://www.ncbi.nlm.nih.gov/pubmed/34609968
http://dx.doi.org/10.1172/JCI142765

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