Dysfunctional TRPM8 signalling in the vascular response to environmental cold in ageing

Ageing is associated with increased vulnerability to environmental cold exposure. Previously, we identified the role of the cold-sensitive transient receptor potential (TRP) A1, M8 receptors as vascular cold sensors in mouse skin. We hypothesised that this dynamic cold-sensor system may become dysfu...

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Detalles Bibliográficos
Autores principales: Thapa, Dibesh, Valente, Joäo de Sousa, Barrett, Brentton, Smith, Matthew John, Argunhan, Fulye, Lee, Sheng Y, Nikitochkina, Sofya, Kodji, Xenia, Brain, Susan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592571/
https://www.ncbi.nlm.nih.gov/pubmed/34726597
http://dx.doi.org/10.7554/eLife.70153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592571/
https://www.ncbi.nlm.nih.gov/pubmed/34726597
http://dx.doi.org/10.7554/eLife.70153

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