Silmitasertib-induced macropinocytosis promoting DDP intracellular uptake to enhance cell apoptosis in oral squamous cell carcinoma

Cisplatin (DDP) is a first-line chemotherapeutic drug applied for the treatment of oral squamous cell carcinoma (OSCC). The anticancer activity of DDP is tightly linked to its intracellular uptake. It is unwise to increase the DDP intake by increasing the dose or shortening the dosing interval becau...

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Detalles Bibliográficos
Autores principales: Song, Shaojuan, Xia, Xin, Qi, Jiajia, Hu, Xiaopei, Chen, Qian, Liu, Jiang, Ji, Ning, Zhao, Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592591/
https://www.ncbi.nlm.nih.gov/pubmed/34766543
http://dx.doi.org/10.1080/10717544.2021.2000677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592591/
https://www.ncbi.nlm.nih.gov/pubmed/34766543
http://dx.doi.org/10.1080/10717544.2021.2000677

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