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Aspirin Exerts Neuroprotective Effects by Reversing Lipopolysaccharide-Induced Secondary Brain Injury and Inhibiting Matrix Metalloproteinase-3 Gene Expression

OBJECTIVE: This study is aimed at exploring the possible neuroprotective mechanism of aspirin and the effect of bacterial endotoxin lipopolysaccharide (LPS) during cerebral ischaemia-reperfusion (CIRP) injury. METHODS: We established three animal models: the CIRP, LPS, and CIRP+LPS models. Mortality...

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Detalles Bibliográficos
Autores principales: Feng, Depeng, Chen, Dezhe, Chen, Tuanzhi, Sun, Xiaoqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592756/
https://www.ncbi.nlm.nih.gov/pubmed/34790277
http://dx.doi.org/10.1155/2021/3682034