Cargando…

Aspirin Exerts Neuroprotective Effects by Reversing Lipopolysaccharide-Induced Secondary Brain Injury and Inhibiting Matrix Metalloproteinase-3 Gene Expression

OBJECTIVE: This study is aimed at exploring the possible neuroprotective mechanism of aspirin and the effect of bacterial endotoxin lipopolysaccharide (LPS) during cerebral ischaemia-reperfusion (CIRP) injury. METHODS: We established three animal models: the CIRP, LPS, and CIRP+LPS models. Mortality...

Descripción completa

Detalles Bibliográficos
Autores principales:	Feng, Depeng, Chen, Dezhe, Chen, Tuanzhi, Sun, Xiaoqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8592756/ https://www.ncbi.nlm.nih.gov/pubmed/34790277 http://dx.doi.org/10.1155/2021/3682034

Ejemplares similares

Momordica charantia Exosome-Like Nanoparticles Exert Neuroprotective Effects Against Ischemic Brain Injury via Inhibiting Matrix Metalloproteinase 9 and Activating the AKT/GSK3β Signaling Pathway
por: Cai, Heng, et al.
Publicado: (2022)

Lipopolysaccharide-Induced Matrix Metalloproteinase-9 Expression Associated with Cell Migration in Rat Brain Astrocytes
por: Yang, Chien-Chung, et al.
Publicado: (2019)

Selective Inhibition of Matrix Metalloproteinase-9 Attenuates Secondary Damage Resulting from Severe Traumatic Brain Injury
por: Hadass, Orr, et al.
Publicado: (2013)

Neuroprotection Exerted by Netrin-1 and Kinesin Motor KIF1A in Secondary Brain Injury following Experimental Intracerebral Hemorrhage in Rats
por: Wang, Jun, et al.
Publicado: (2018)

6-O-angeloylplenolin exerts neuroprotection against lipopolysaccharide-induced neuroinflammation in vitro and in vivo
por: Zhou, Yi-le, et al.
Publicado: (2019)

Matrix Metalloproteinase 9 Exerts Antiviral Activity against Respiratory Syncytial Virus
por: Dabo, Abdoulaye J., et al.
Publicado: (2015)

Lipopolysaccharide induces inflammatory microglial activation through CD147-mediated matrix metalloproteinase expression
por: Yao, Chunyan, et al.
Publicado: (2022)

Neuroprotective Effects of Collagen-Glycosaminoglycan Matrix Implantation following Surgical Brain Injury
por: Chen, Jia-Hui, et al.
Publicado: (2019)

Lipopolysaccharide Effect on Vascular Endothelial Factor and Matrix Metalloproteinases in Leukemic Cell Lines In vitro
por: Hajighasemi, Fatemeh, et al.
Publicado: (2015)

Expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in the hair cycle
por: HOU, CHUN, et al.
Publicado: (2016)

Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury
por: Chen, Guobing, et al.
Publicado: (2020)

Dynamics of cerebrospinal fluid levels of matrix metalloproteinases in human traumatic brain injury
por: Minta, Karolina, et al.
Publicado: (2020)

Matrix Metalloproteinases, Synaptic Injury, and Multiple Sclerosis
por: Szklarczyk, Arek, et al.
Publicado: (2010)

Matrix metalloproteinases in liver injury, repair and fibrosis
por: Duarte, Sergio, et al.
Publicado: (2015)

Smurf2 exerts neuroprotective effects on cerebral ischemic injury
por: Liu, Haibin, et al.
Publicado: (2021)

Neuropeptides Exert Neuroprotective Effects in Alzheimer's Disease
por: Chen, Xin-Yi, et al.
Publicado: (2019)

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity
por: Karsdal, Morten A, et al.
Publicado: (2008)

Levels of matrix metalloproteinase-8 and cold test in reversible and irreversible pulpitis
por: Aguirre-López, Eva Concepción, et al.
Publicado: (2020)

A nutrient mixture reduces the expression of matrix metalloproteinases in an animal model of spinal cord injury by modulating matrix metalloproteinase-2 and matrix metalloproteinase-9 promoter activities
por: ZHANG, HONGQI, et al.
Publicado: (2014)

The matrix metalloproteinase inhibitor RS-130830 attenuates brain injury in experimental pneumococcal meningitis
por: Liechti, Fabian D, et al.
Publicado: (2015)

Matrix Metalloproteinase Expression in Contusional Traumatic Brain Injury: A Paired Microdialysis Study
por: Guilfoyle, Mathew R., et al.
Publicado: (2015)

Matrix Metalloproteinase Activity in Pediatric Acute Lung Injury
por: Kong, Michele YF, et al.
Publicado: (2008)

Matrix Metalloproteinase-10 in Kidney Injury Repair and Disease
por: Sun, Xiaoli, et al.
Publicado: (2022)

Functional relationship between matrix metalloproteinase-11 and matrix metalloproteinase-14
por: Buache, Emilie, et al.
Publicado: (2014)

Syndecan-1 Shedding by Matrix Metalloproteinase-9 Signaling Regulates Alveolar Epithelial Tight Junction in Lipopolysaccharide-Induced Early Acute Lung Injury
por: Zhang, Dong, et al.
Publicado: (2021)

Rosiglitazone exerts neuroprotective effects via the suppression of neuronal autophagy and apoptosis in the cortex following traumatic brain injury
por: YAO, JUNCHAO, et al.
Publicado: (2015)

Differential Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Thioacetamide-Induced Chronic Liver Injury
por: Park, Soo Young, et al.
Publicado: (2010)

Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis
por: Gao, Wei, et al.
Publicado: (2016)

RGFP966 exerts neuroprotective effect via HDAC3/Nrf2 pathway after surgical brain injury in rats
por: Gu, Hai-Ping, et al.
Publicado: (2023)

Matrix metalloproteinases and epileptogenesis
por: Ikonomidou, Chrysanthy
Publicado: (2014)

Matrix Metalloproteinases and Glaucoma
por: Kim, Moo Hyun, et al.
Publicado: (2022)

New Insights into the Roles of Metalloproteinases in Neurodegeneration and Neuroprotection
por: Turner, A.J., et al.
Publicado: (2007)

Osthole confers neuroprotection against cortical stab wound injury and attenuates secondary brain injury
por: Xia, Yang, et al.
Publicado: (2015)

SS-31 Provides Neuroprotection by Reversing Mitochondrial Dysfunction after Traumatic Brain Injury
por: Zhu, Yihao, et al.
Publicado: (2018)

Erythropoietin administration exerted neuroprotective effects against cardiac ischemia/reperfusion injury
por: Chunchai, Titikorn, et al.
Publicado: (2022)

Can Natural Products Exert Neuroprotection without Crossing the Blood–Brain Barrier?
por: Leclerc, Manon, et al.
Publicado: (2021)

Enhancement of matrix metalloproteinases 2 and 9 accompanied with neurogenesis following collagen glycosaminoglycan matrix implantation after surgical brain injury
por: Hsu, Wei-Cherng, et al.
Publicado: (2018)

Matrix metalloproteinases and their inhibitors in human traumatic spinal cord injury
por: Buss, Armin, et al.
Publicado: (2007)

Extracellular matrix metalloproteinase inducer in brain ischemia and intracerebral hemorrhage
por: Liu, Yang, et al.
Publicado: (2022)

Methylene blue exerts a neuroprotective effect against traumatic brain injury by promoting autophagy and inhibiting microglial activation
por: ZHAO, MINGFEI, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c9bmrn2iq9hrd99m4vafsm714e